Does raising estrogen impact cognitive performance during menopause?
Originally at news.google.com
Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.
Why it matters for dental
Dentists treating menopausal patients may see self-reported improvements in memory, concentration, and verbal fluency after hormone therapy, which could change exam compliance and treatment-plan discussions.
Key points
- Researchers assigned 20 healthy menopausal women a 12-month regimen of estriol and progesterone, after which participants self-reported gains in brain fog, concentration, working memory, processing speed, verbal memory, and problem-solving.
- In ovariectomized and estrogen-receptor-beta-deleted midlife female mice, one month of estriol treatment lowered hippocampal ENO1 expression, glial activation, and synaptic loss.
- The source states that further studies are required to determine the safety and efficacy of estriol treatment in this patient population.
- The article notes that estrogen receptors may be used to reduce toxicity in other organ systems, with potential relevance to oral tissues.
Who should care
Read the original on ADA News
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