- MEDIUM
- Research
- Tier 1
- Peer-Reviewed Research
Tube and tooth fragment skinfold models for pulp neovascularization studies
- Source
- Journal of Dental Research (JDR)
- Author
- D. Dasi, I.J. de Souza Araujo, Y. Zhang, V. Vikram, W. Zhang, J. Liu, L.L. Munn, G.T.-J. Huang
- Originally at
- journals.sagepub.com(opens in a new tab)
Summary and scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol. Not the original publisher.
Why it matters for dental
Researchers developed two in vivo models to study pulp neovascularization, extending prior in vitro work with dental pulp stem cell-derived endothelial-like cells in fibrin gel.
Key points
- 01
Researchers extended an in vitro tube model to in vivo settings using tube and tooth fragment skinfold models.
- 02
Researchers used human dental pulp stem cell-derived endothelial-like cells suspended in fibrin gel to simulate root canal space.
- 03
Researchers performed a qualitative assessment of vascular-like structure formation in these models.
- 04
Researchers built on previous in vitro findings that dental pulp stem cell-derived endothelial-like cells can form vascular-like structures in fibrin gel.
Who should care
- Academia / research
- Specialist
Read the original
Journal of Dental Research (JDR)
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