The role of periostin in mechanotransduction in musculoskeletal and periodontal tissues: A scoping review
Originally at sciencedirect.com
Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.
Why it matters for dental
Periodontal specialists and academics may gain mechanistic insight into how mechanical forces regulate periostin in the periodontal ligament, potentially informing future regenerative protocols and orthodontic force management.
Key points
- Scoping review published in Journal of Dentistry (Vol 175) synthesizes current evidence on periostin expression under load in both musculoskeletal and periodontal tissues.
- Authors map mechanotransduction pathways linking periostin to extracellular-matrix remodeling, relevant to periodontal ligament adaptation during orthodontic tooth movement.
- Review highlights gaps in human clinical data, signaling need for targeted studies before periostin can be used as a biomarker or therapeutic target in periodontal regeneration.
- Effective publication date December 2026 implies a forthcoming evidence base rather than immediate clinical guideline changes.
Who should care
Read the original on Journal of Dentistry
Full reporting and any paywall content live on sciencedirect.com. We summarize and score; we do not republish.
Related
- ·Business
US Oral Surgery Management exec on M&A: ‘We’ve had to be even more disciplined’
- ·Research
Vertical dimension of occlusion restoration using a digital injectable composite resin technique: A 5-year clinical follow-up
- ·Research
A digitally guided workflow integrating tooth preparation and restoration positioning for minimally invasive veneer and partial-coverage restorations: A dental technique
- ·Research
Effect of a Novel Bioceramic Solvent on Apical Patency during Nonsurgical Endodontic Retreatment: An Ex Vivo Study