HIGHResearchTier 1

Pulpal calcification: A systematic review and meta-analysis evaluating differences among repair materials and the association with vital pulpal therapy success

SourceJournal of the American Dental Association (JADA)Tier 1Peer-Reviewed Research

Originally at sciencedirect.com

Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.

Why it matters for dental

Endodontists and restorative dentists now have quantified evidence that material choice after vital pulp therapy directly affects long-term pulpal calcification and treatment success, guiding material selection for better pulp preservation.

Key points

  • Meta-analysis of 23 studies (n=2,317 teeth) showed MTA and Biodentine produced significantly less dystrophic calcification than calcium hydroxide after vital pulp therapy (OR 0.41, 95 % CI 0.28-0.59).
  • Calcification severity was graded radiographically; teeth restored with MTA had 31 % lower odds of complete canal obliteration at 36 months, preserving future endodontic access.
  • Success rates (absence of symptoms, PAI ≤ 2, positive cold test) remained > 92 % with silicate cements versus 78 % with calcium hydroxide at the same follow-up interval.
  • The authors recommend switching from calcium hydroxide to MTA or Biodentine as the first-line direct pulp-capping agent in permanent teeth when vital pulp therapy is indicated.

Who should care

SpecialistAcademia

Read the original on Journal of the American Dental Association (JADA)

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