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The Bell BriefFrom Dr. Jennifer Bell, DDS
HIGHResearchTier 1

Palatal Donor‐Site Healing and Patient‐Reported Outcome Measures Following Chitosan and Injectable Platelet‐Rich Fibrin‐Enriched Chitosan Application Compared with Gelatine Sponge: A Three‐Arm Randomised Controlled Clinical Trial

SourceJournal of Clinical PeriodontologyTier 1Peer-Reviewed Research

By Ayse Ege Selman, Bahar Alkaya, Burcu Karaduman, Mustafa Ozcan, Mehmet Cenk Haytac

Originally at onlinelibrary.wiley.com

Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.

Why it matters for dental

Periodontists and implant surgeons placing soft-tissue grafts should note that chitosan and i-PRF-enriched chitosan dressings significantly accelerated palatal donor-site healing and lowered patient-reported pain compared with gelatin sponge, potentially shortening chair time and post-op visits.

Key points

  • Three-arm RCT (n = 60) in Journal of Clinical Periodontology found chitosan and i-PRF-chitosan groups had faster complete epithelialization at 2 weeks vs. gelatin sponge controls.
  • Patient-reported pain scores (VAS) and analgesic intake were statistically lower in both chitosan arms through post-op day 7.
  • No donor-site infections or delayed bleeding occurred in any group; chitosan materials resorbed without secondary procedures.
  • Results apply to free-gingival and connective-tissue graft cases; practices performing ≥5 palatal harvests/month may see workflow and patient-satisfaction gains.

Who should care

SpecialistAcademia

Read the original on Journal of Clinical Periodontology

Full reporting and any paywall content live on onlinelibrary.wiley.com. We summarize and score; we do not republish.

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