HIGHResearchTier 1

Efficacy and clinical indications of adjunctive chlorhexidine mouthrinses in nonsurgical

SourcePeriodontology 2000Tier 1Peer-Reviewed Research

By Luca Coccoluto, Luca Antonelli, Ivana Crescenzi, Marco Crescenzi, Roberto Rotundo

Originally at onlinelibrary.wiley.com

Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.

Why it matters for dental

Periodontists, general dentists, and hygienists treating periodontitis should note that adjunctive chlorhexidine rinses yield measurable reductions in pocket depth and bleeding on probing when used with both nonsurgical and surgical therapy.

Key points

  • Systematic review and meta-analysis published in Periodontology 2000 synthesizes evidence on chlorhexidine mouthrinses used with scaling/root planing and flap surgery.
  • Chlorhexidine demonstrated statistically significant adjunctive benefits versus controls for probing-depth reduction and bleeding indices.
  • Findings apply to both open-flap debridement and closed nonsurgical protocols, supporting inclusion decisions in periodontal treatment plans.
  • No effective date stated; clinicians may consider updating rinse protocols in active periodontitis cases based on the meta-analysis conclusions.

Who should care

SpecialistAssociateAcademia

Read the original on Periodontology 2000

Full reporting and any paywall content live on onlinelibrary.wiley.com. We summarize and score; we do not republish.

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