HIGHResearchTier 1
Diagnosed dental diseases, tooth loss
SourceJournal of Clinical PeriodontologyTier 1Peer-Reviewed Research
By Qiaofeng Zhong, Zengliang Ruan, Li Yin, Hans‐Olov Adami, Weimin Ye
Originally at onlinelibrary.wiley.com
Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.
Why it matters for dental
Swedish national registry data link diagnosed caries, periodontitis, and fewer remaining teeth to higher primary liver cancer incidence, giving U.S. dental professionals an additional data point when counseling patients on systemic disease associations.
Key points
- Caries showed HR 1.15 and periodontitis HR 1.25 for primary liver cancer in a cohort of 5,893,325 adults.
- A dose-response pattern was observed: hazard ratios rose from 1.15 to 1.84 as remaining teeth dropped below 27.
- Caries was linked to non-hepatocellular carcinoma primary liver cancer; periodontitis was linked to hepatocellular carcinoma.
- Sibling-controlled analyses yielded results consistent with the overall cohort findings.
Who should care
AcademiaSpecialist
Read the original on Journal of Clinical Periodontology
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