- MEDIUM
- Research
- Tier 1
- Peer-Reviewed Research
Anti-infective treatment of severe periodontitis: hypothetical implementation
- Source
- Periodontology 2000
- Author
- Jørgen Slots
- Originally at
- onlinelibrary.wiley.com(opens in a new tab)
Summary and scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol. Not the original publisher.
Why it matters for dental
Periodontists and hygienists treating severe periodontitis (stage 3/4) should weigh a proposed two-visit anti-infective protocol that combines systemic antivirals, antibiotics, and local biofilm antiseptics with traditional mechanical care.
Key points
- 01
Periodontology 2000 article proposes valacyclovir on days 1-4, a two-day pause, ciprofloxacin-metronidazole on days 7-11, and sodium hypochlorite irrigation during ultrasonic scaling.
- 02
The protocol calls for two office visits on treatment days 1 and 7, with dental hygienists performing much of the therapy.
- 03
Article states the approach is intended as either a standalone regimen or an adjunct to conventional periodontal therapy for severe periodontitis and peri-implantitis.
- 04
Authors note the regimen's potential relevance to periodontal-related systemic diseases but call for further research before clinical adoption.
Who should care
- Specialist
- Academia / research
Read the original
Periodontology 2000
Full reporting and any paywalled content live on onlinelibrary.wiley.com. We summarize and score; we do not republish.