MEDIUMResearchTier 1
An exploratory longitudinal analysis of salivary host, bacterial
SourceJournal of Clinical PeriodontologyTier 1Peer-Reviewed Research
By Chun Liu, Jenny Wang, Andrew Lai, Carlos Salomon, Chaminda Jayampath Seneviratne, Sašo Ivanovski, Pingping Han
Originally at onlinelibrary.wiley.com
Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.
Why it matters for dental
Periodontists and hygiene teams treating Stage III/IV cases may gain a non-invasive salivary test to monitor treatment response after non-surgical therapy.
Key points
- 25 Stage III/IV periodontitis patients showed lowered periodontal parameters at 3 and 6 months after non-surgical periodontal therapy.
- Host salivary extracellular vesicles carried higher IL-4, IL-12, and IL-9 cytokines at both 3- and 6-month visits compared with baseline.
- Bacterial extracellular vesicles from Filifactor alocis, Tannerella forsythia, Treponema denticola, Porphyromonas gingivalis, and Fusobacterium nucleatum declined in saliva and plaque after therapy.
- At 6 months, fungal extracellular vesicles from Malassezia arunalokei decreased while Candida parapsilosis vesicles increased in saliva.
Who should care
SpecialistAcademia
Read the original on Journal of Clinical Periodontology
Full reporting and any paywall content live on onlinelibrary.wiley.com. We summarize and score; we do not republish.