MEDIUMClinicalTier 1

Phosphate-assisted hydration of tricalcium silicate promotes hydroxyapatite formation and enhances osteogenic potential

SourceJournal of DentistryTier 1Peer-Reviewed Research

Originally at sciencedirect.com

Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.

Why it matters for dental

Tricalcium silicate cements that are hydrated with phosphate show accelerated hydroxyapatite formation, which may improve the osteogenic response around root-end fillings and pulp-capping sites.

Key points

  • Phosphate-assisted hydration of tricalcium silicate produced hydroxyapatite more rapidly than standard hydration in bench tests.
  • In vitro osteoblast assays indicated higher alkaline-phosphatase activity and mineralized nodule formation with the phosphate-modified cement.
  • The findings could influence future formulations of MTA-type materials used in endodontics and vital pulp therapy.
  • No regulatory clearance or clinical outcome data are provided; commercial availability is not addressed.

Who should care

SpecialistAssociate

Read the original on Journal of Dentistry

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