Effect of Hyaluronic Acid on Palatal Wound Healing—A Randomized Crossover Clinical Trial
By Madeleine Dahi, Sara Amash, Kristina Bertl, Florian Beck, Patrick Heimel, Andreas Stavropoulos
Originally at onlinelibrary.wiley.com
Summary & scoring by The Bell Brief (Dr. Jennifer Bell) using the Drill-Down Protocol (Drill-Down Score) — not the original publisher.
Why it matters for dental
Randomized crossover trial shows hyaluronic acid accelerates palatal wound closure after connective-tissue grafting but does not alter final healing quality.
Key points
- HA gel applied to the palate improved re-epithelialization and reduced patient-reported pain scores vs placebo in a crossover RCT of 20 patients.
- Faster healing at the palatal site may shorten the interval before the next surgical phase or prosthetic delivery in implant cases.
- No adverse events were linked to HA, suggesting an easy-to-adopt adjunct for practices already performing connective-tissue grafts.
- Small single-center study; larger multi-center trials needed before widespread protocol changes.
Who should care
Read the original on Clinical Oral Implants Research
Full reporting and any paywall content live on onlinelibrary.wiley.com. We summarize and score; we do not republish.
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